Antibody (crazyrems) Mac OS
  1. Antibody (crazyrems) Mac Os Update
  2. Mac Os Catalina
  3. Antibody (crazyrems) Mac Os X
  4. Antibody (crazyrems) Mac Os Download

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To see which PTS are accredited according to the international standard ISO, please view our time schedule. The antibody mining toolbox An open source tool for the rapid analysis of antibody repertoires Sara D’Angelo1, Jacob Glanville2. (Microsoft Windows, Mac OS X, Linux), on standard personal computers, and sequence analysis of 1–2 million reads can be accomplished in 10–15 min, a fraction of the time of competing software. Mar 04, 2021 The Best Mac Antivirus Protection for 2021. Despite what you may have heard, your Apple computer is not immune to malware. We test the top contenders to identify those offering the best Mac. Anti-MAC1 Antibody Products. MAC1 is a reported alias of the human protein 'integrin subunit alpha M', encoded by the gene ITGAM. Anti-MAC1 antibodies are available from several suppliers. Other names for this gene include CD11b, IGAM, and integrin alpha M. The full protein is reported to be 1152 amino acid residues in length.

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Pricing & Availability
Clone
M3/84 (See other available formats)
Other Names
CD107b, LAMP-2
Isotype
Rat IgG1, κ
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Product Citations
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Cat # Size Price Quantity Avail. Save
108501 50 µg $70
108502 500 µg $220
Description

Mac-3 is a 110 kD type I membrane glycoprotein, also known as CD107b and LAMP-2. It is expressed on lysosomal membranes and the plasma membrane of macrophages and some myeloid cell lines. In the bone marrow, few cells display Mac-3 antigen on the surface, but a large proportion express Mac-3 in the cytoplasm. CD107b has been identified as a ligand for galaptin, an S-type lectin present in the extracellular matrix. Mac-3/CD107b is upregulated in some tumors and increased expression has been correlated with enhanced metastatic potential.

Product Details Technical data sheet

Product Details

Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Membrane glycoproteins from C57BL/6 mouse peritoneal exudate cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, ICC, IHC-P, IHC-F - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Mac
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation1-4 and immunohistochemical staining of acetone-fixed frozen sections5,6 and paraformaldehyde-fixed paraffin-embedded sections9-11.

Application References
(PubMed link indicates BioLegend citation)
  1. Springer TA. 1981. J. Biol. Chem. 256:3833. (IP)
  2. Ho MK, et al. 1983. J. Biol. Chem. 258:636. (IP)
  3. Chen JW, et al. 1985. J. Cell Biol. 101:85. (IP)
  4. Ralph P, et al. 1983. J. Immunol. 130:108. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Kano M, et al. 1998. Transplantation 65:837. (IHC)
  7. Terrazas LI,et al.2005. Int J Parasitol. 35:1349. PubMed
  8. Hayashida A, et al. 2011. J. Biol Chem. 286:3288. PubMed
  9. Vollmar P, et al. 2010. J. Immunol. 185:6338. (IHC)
  10. Odorisio T, et al. 2002. J. Cell Sci. 115:2559. (IHC)
  11. Nessler S, et al. 2007. Brain 130:2186. (IHC)
Product Citations
  1. Orimo T, et al. 2019. Int Immunol. 31:657. PubMed
  2. Kälin S et al. 2017. Cell metabolism. 26(3):475-492 . PubMed
  3. Sonner JK, et al. 2019. Nat Commun. 3.803472222. PubMed
  4. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  5. Hayashida A, et al. 2011. J Biol Chem. 286:3288. PubMed
  6. Luo Y, et al. 2017. Cell Res. 10.1038/cr.2017.8. PubMed
RRID
AB_313382 (BioLegend Cat. No. 108501)
AB_313383 (BioLegend Cat. No. 108502)

Antigen Details

Structure
110 kD
Distribution

Antibody (crazyrems) Mac Os Update

Macrophages, some myeloid cell lines

Function
Differentiation and activation
Cell Type
Macrophages
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Springer TA. 1981. J. Biol. Chem. 256:3833.
2. Ho MK, et al. 1983. J. Biol. Chem. 258:636.
3. Ralph P, et al. 1983. J. Immunol. 130:108.

Gene ID

Mac Os Catalina

UniProt
View information about CD107b on UniProt.org

Documentation

Related Protocols

Related Pages & Pathways

Pages

Other Formats

Antibody (crazyrems) Mac Os X

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Version: 2 Revision Date: 10/22/2013